Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924076 | 0.80 | BRD4 (1.00) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL1142084 | 0.78 | BRD4 (0.78) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL8676619 | 0.76 | BRD4 (0.62) | BRD4KMT2AMEN1CYP19A1LMNA | |
| SCHEMBL28757819 | 0.74 | ALDH1A1 (0.49) | BRD4ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL8047911 | 0.73 | BRD4 (0.51) | BRD4PPIAKDM4ETDP1L3MBTL1 | |
| SCHEMBL9687384 | 0.73 | BRD4 (0.47) | BRD4ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL8616388 | 0.72 | ALDH1A1 (0.49) | BRD4ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL13192251 | 0.72 | BRD4 (0.76) | BRD4KMT2AMEN1CYP19A1ALDH1A1 | |
| SCHEMBL5736091 | 0.71 | RAD52 (0.46) | BRD4ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL7646955 | 0.71 | BRD4 (0.74) | BRD4KMT2AMEN1CYP19A1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |