Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261455 | 0.90 | ALDH1A1 (0.45) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11441661 | 0.82 | MAPT (0.61) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12121503 | 0.81 | PLK1 (0.47) | MAPTLMNANPSR1ALDH1A1ALPG | |
| SCHEMBL12778023 | 0.81 | KCNH2 (0.48) | MAPTLMNAALDH1A1KCNH2 | |
| SCHEMBL10489192 | 0.81 | KAT8 (0.56) | MAPTLMNANPSR1ALDH1A1KCNH2 | |
| SCHEMBL9100894 | 0.81 | KCNH2 (0.51) | MAPTLMNAALDH1A1KCNH2 | |
| SCHEMBL8744027 | 0.81 | KCNH2 (0.48) | LMNAALDH1A1KCNH2 | |
| SCHEMBL9586705 | 0.81 | KAT8 (0.56) | MAPTLMNANPSR1ALDH1A1KCNH2 | |
| SCHEMBL6365845 | 0.81 | KCNH2 (0.51) | MAPTLMNAALDH1A1KCNH2 | |
| SCHEMBL7041547 | 0.81 | KAT8 (0.56) | MAPTLMNANPSR1ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168219-A | Electrode for measurement of ionic activity, sensor film therefor and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 1979-09-18 | — | — | US | disclosed |