Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183841 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SIGMAR1BACE1 | |
| SCHEMBL11183844 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SIGMAR1BACE1 | |
| SCHEMBL11252676 | 0.96 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3SIGMAR1BACE1 | |
| SCHEMBL11185274 | 0.84 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3SIGMAR1BACE1 | |
| SCHEMBL11185272 | 0.84 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3SIGMAR1BACE1 | |
| SCHEMBL11534979 | 0.84 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3BACE1CTSD | |
| SCHEMBL11187799 | 0.84 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3BACE1CTSD | |
| SCHEMBL11187797 | 0.84 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3BACE1CTSD | |
| SCHEMBL11539220 | 0.84 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3BACE1CTSD | |
| SCHEMBL11192497 | 0.84 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150135-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | disclosed |