Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187799 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1BACE1 | |
| SCHEMBL11187797 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1BACE1 | |
| SCHEMBL11247408 | 0.96 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1BACE1 | |
| SCHEMBL11535339 | 0.86 | LIG1 (0.38) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL11539184 | 0.86 | LIG1 (0.38) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL11535340 | 0.86 | LIG1 (0.38) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL11183841 | 0.84 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3BACE1KMT2A | |
| SCHEMBL11183844 | 0.84 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3BACE1KMT2A | |
| SCHEMBL11539811 | 0.84 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3BACE1KMT2A | |
| SCHEMBL11532954 | 0.80 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150135-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | disclosed |