Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.66 |
| ▸ | CA5A | P35218 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 14/20 | 0.65 |
| ▸ | CA12 | O43570 | 12/20 | 0.65 |
| ▸ | CA9 | Q16790 | 12/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.65 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172200 | 0.95 | CA2 (0.66) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL2868538 | 0.88 | CA2 (0.58) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL28474520 | 0.86 | TSHR (0.61) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL11685973 | 0.86 | CA2 (0.56) | CA2CA5ACA1CA12CA9 | |
| Bromide SCHEMBL25249139 | 0.85 | TSHR (0.59) | CA2CA5ACA1CA12CA9 | |
| Bromide SCHEMBL29431933 | 0.85 | TSHR (0.59) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL13822319 | 0.83 | CA2 (0.53) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL15055314 | 0.82 | CA2 (0.51) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL21410215 | 0.82 | CA2 (0.51) | CA2CA5ACA1CA12CA9 | |
| SCHEMBL21410225 | 0.82 | CA2 (0.51) | CA2CA5ACA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172089-A | COMPLEMENT INHIBITOR TRI- OR HEXA-PHENYL ESTER INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4117003-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4001201-A | SULFONYL- | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |