Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537810 | 0.84 | NR3C1 (0.44) | NR3C1PGRNR3C2ARGAA | |
| SCHEMBL13295542 | 0.83 | CASR (0.53) | GAAMGAMSIMGAM2CASR | |
| SCHEMBL14205688 | 0.83 | CASR (0.53) | GAAMGAMSIMGAM2CASR | |
| SCHEMBL3172692 | 0.82 | SLC2A1 (0.49) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL3165454 | 0.82 | EPHX2 (0.43) | NR3C1PGRNR3C2ARL3MBTL1 | |
| Benzene SCHEMBL11146992 | 0.82 | CASR (0.54) | GAAMGAMSIMGAM2CASR | |
| SCHEMBL1050770 | 0.82 | CASR (0.54) | GAAMGAMSIMGAM2CASR | |
| SCHEMBL11535826 | 0.74 | CNR1 (0.44) | CYP19A1CNR1 | |
| SCHEMBL11538348 | 0.73 | SLC6A2 (0.60) | CASRMTNR1AMTNR1BCYP19A1CYP11B1 | |
| SCHEMBL31409228 | 0.72 | SMN1; SMN2 (0.56) | GAAMGAMSIMGAM2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |