Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 17/20 | 0.45 |
| ▸ | MPEG1 | Q2M385 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543633 | 0.89 | ALDH1A1 (0.45) | PTPN1ALOX5ALDH1A1MAPTTHRB | |
| Acequinocyl SCHEMBL4052105 | 0.87 | PTPN1 (0.48) | PTPN1ALOX5MPEG1 | |
| SCHEMBL11541723 | 0.87 | PTPN1 (0.48) | PTPN1ALOX5MPEG1 | |
| Acequinocyl SCHEMBL28131 | 0.87 | PTPN1 (0.48) | PTPN1ALOX5MPEG1 | |
| Acequinocyl SCHEMBL29368518 | 0.87 | PTPN1 (0.48) | PTPN1ALOX5MPEG1 | |
| SCHEMBL11539787 | 0.86 | PTPN1 (0.47) | PTPN1ALOX5MPEG1MAPT | |
| SCHEMBL11537827 | 0.86 | PTPN1 (0.47) | PTPN1ALOX5MPEG1MAPT | |
| SCHEMBL11540034 | 0.85 | POLM (0.47) | PTPN1ALOX5MPEG1 | |
| SCHEMBL11539908 | 0.85 | PTPN1 (0.46) | PTPN1ALOX5MPEG1ALDH1A1THRB | |
| SCHEMBL11544333 | 0.85 | POLM (0.47) | PTPN1ALOX5MPEG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143157-A | Miticidal and aphicidal method utilizing 2-higher alkyl-3-hydroxy-1'4-naphthoquinone carboxylic acid esters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4107325-A | PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4082848-A | MITICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4055661-A | Miticidal and aphicidal method utilizing 2-higher alkyl-3-hydroxy-1,4-naphthoquinone carboxylic acid esters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4053634-A | MITICIDAL AND APHICIDAL METHOD UTILIZING 2-HIGHER ALKYL-3-HYDROXY-1,4-NAPHTHOQUINONE CARBOXYLIC ACID ESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-11 | — | — | US | disclosed |