Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138212 | 0.90 | CYP2C9 (0.59) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11541420 | 0.90 | CYP2C9 (0.65) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11539857 | 0.89 | CYP2C9 (0.57) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11541052 | 0.89 | CYP2C9 (0.57) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11538281 | 0.86 | CYP2C9 (0.55) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11543646 | 0.85 | CYP2C9 (0.56) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11421506 | 0.84 | CYP2C9 (0.53) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL9209426 | 0.84 | TDP1 (0.62) | MAPTTSHRTP53TDP1PTGDR2 | |
| SCHEMBL11540254 | 0.83 | CYP2C9 (0.58) | CYP2C9MAPTTSHRALDH1A1NPSR1 | |
| SCHEMBL11265896 | 0.82 | CYP2C9 (0.54) | CYP2C9MAPTTSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058559-A | HYPOTENSIVE AGENTS, DIURETICS, URICOSURIC AGENTS | ABBOTT LABORATORIES (US) | 1977-11-15 | — | — | US | claimed |
| US-9624505-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-9624505-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2145007-B1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| US-20160002662-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | PIONEER HI-BRED INTERNATIONAL, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20160002662-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | PIONEER HI-BRED INTERNATIONAL, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9062284-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2015-06-23 | — | — | US | disclosed |
| US-9062284-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2015-06-23 | — | — | US | disclosed |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-8278505-B2 | Herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES, LLC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278505-B2 | Herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES, LLC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100251432-A1 | Novel Herbicide Resistance Genes | DOW AGROSCIENCES LLC (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100251432-A1 | Novel Herbicide Resistance Genes | DOW AGROSCIENCES LLC (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2008141154-A2 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2008-11-20 | — | — | WO | disclosed |
| US-4166819-A | HYPOTENSIVES, DIURETICS | ABBOTT LABORATORIES (US) | 1979-09-04 | — | — | US | disclosed |
| US-4058559-A | HYPOTENSIVE AGENTS, DIURETICS, URICOSURIC AGENTS | ABBOTT LABORATORIES (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | AADAC, AGXT, HPD | CYP2C9 382/4885MAPT 4760/4885TSHR 3852/4885 |
| US-20100251432-A1 | Novel Herbicide Resistance Genes | AADAC, AGXT, DDT | CYP2C9 403/4885MAPT 4666/4885TSHR 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.