Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540936 | 0.89 | FABP6 (0.45) | FABP6ABL1PLAUALDH1A1NPSR1 | |
| SCHEMBL6112815 | 0.82 | ABL1 (0.61) | FABP6ABL1PLAUHTR3EHTR3B | |
| SCHEMBL11477127 | 0.82 | NPSR1 (0.66) | PLAUTDP1HSP90AA1ESR2ALDH1A1 | |
| Bromide SCHEMBL6125570 | 0.81 | ABL1 (0.59) | FABP6ABL1PLAUHTR3EHTR3B | |
| SCHEMBL725578 | 0.80 | FABP6 (0.66) | FABP6ABL1PLAUHTR3EHTR3B | |
| SCHEMBL9205488 | 0.80 | PSMB8 (0.50) | ABL1TDP1HSP90AA1ESR2ALDH1A1 | |
| SCHEMBL9209540 | 0.80 | SMN1; SMN2 (0.49) | TDP1HSP90AA1ESR2ALDH1A1APEX1 | |
| SCHEMBL8283877 | 0.79 | PKN1 (0.64) | FABP6ABL1PLAUTDP1HSP90AA1 | |
| SCHEMBL1261208 | 0.79 | ABL1 (0.72) | FABP6ABL1PLAUHTR3EHTR3B | |
| SCHEMBL12685844 | 0.79 | ABL1 (0.68) | FABP6ABL1PLAUHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |