Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205475 | 0.90 | PSMB8 (0.40) | PSMB8NPSR1HSD17B3ALDH1A1HPGD | |
| SCHEMBL12855143 | 0.82 | PKN1 (0.61) | PSMB8HSP90AA1ESR2TDP1PKN1 | |
| SCHEMBL11540940 | 0.80 | FABP6 (0.58) | HSP90AA1ESR2TDP1APEX1NPSR1 | |
| SCHEMBL9198723 | 0.79 | PSMB8 (0.48) | PSMB8HSP90AA1ESR2TDP1PKN1 | |
| SCHEMBL11477127 | 0.78 | NPSR1 (0.66) | HSP90AA1ESR2TDP1APEX1NPSR1 | |
| SCHEMBL9209540 | 0.76 | SMN1; SMN2 (0.49) | HSP90AA1ESR2TDP1APEX1PKN1 | |
| SCHEMBL3790268 | 0.71 | CTNNB1 (0.72) | TDP1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL9198716 | 0.69 | PSMB8 (0.39) | PSMB8ALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL12647219 | 0.69 | HSP90AA1 (0.69) | HSP90AA1ESR2TDP1PKN1PKN2 | |
| SCHEMBL11540936 | 0.69 | FABP6 (0.45) | NPSR1HSD17B3ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656891-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994004509-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-03-03 | — | — | WO | disclosed |