Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544661 | 0.86 | CES1 (0.54) | CES1PTPN1ESRRGPOLBSRC | |
| SCHEMBL11543720 | 0.85 | CES1 (0.40) | CES1PTPN1ESRRGPOLBSRC | |
| SCHEMBL1999101 | 0.81 | CES1 (0.56) | CES1SRCCYP2C19HIF1ATSHR | |
| SCHEMBL11549447 | 0.75 | CES1 (0.41) | CES1PTPN1POLBSRCCYP2C19 | |
| SCHEMBL11544295 | 0.73 | CES1 (0.49) | CES1PTPN1POLBSRCCYP2C19 | |
| SCHEMBL11746305 | 0.73 | CES1 (0.55) | CES1POLBSRCCYP2C19HIF1A | |
| SCHEMBL1487886 | 0.73 | CES1 (0.65) | CES1SRCCYP2C19HIF1ATSHR | |
| SCHEMBL11540824 | 0.72 | CES1 (0.51) | CES1PTPN1POLBSRCCYP2C19 | |
| SCHEMBL13148475 | 0.72 | CES1 (0.50) | CES1ESRRGSRCCYP2C19HIF1A | |
| SCHEMBL2842170 | 0.72 | CES1 (0.53) | CES1ESRRGPOLBSRCCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |