Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543025 | 0.90 | NPC1 (0.37) | CES1PTPN1SMN1; SMN2POLBLMNA | |
| SCHEMBL11543720 | 0.88 | CES1 (0.40) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11540824 | 0.86 | CES1 (0.51) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11547495 | 0.85 | CES1 (0.40) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11540703 | 0.82 | CES1 (0.38) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11541015 | 0.75 | CES1 (0.43) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11548159 | 0.74 | CES1 (0.47) | CES1PTPN1TSHRKIF11 | |
| SCHEMBL11545782 | 0.74 | CES1 (0.49) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11544661 | 0.72 | CES1 (0.54) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL9346018 | 0.72 | CES1 (0.47) | CES1PTPN1SMN1; SMN2POLBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |