Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542125 | 1.00 | MAPT (0.44) | MAPTHSP90AA1CDK5CDK5R1NCOA1 | |
| SCHEMBL12210777 | 0.81 | MEN1 (0.45) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL2062631 | 0.79 | MEN1 (0.55) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11582542 | 0.78 | ALDH1A1 (0.43) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11582537 | 0.78 | ALDH1A1 (0.43) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL14129105 | 0.78 | PIK3CD (0.40) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| Formaldehyde SCHEMBL28235065 | 0.77 | MEN1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11743813 | 0.74 | PIK3CA (0.43) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL17018289 | 0.74 | MAPT (0.43) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11621739 | 0.74 | KDM4E (0.45) | MAPTCDK5CDK5R1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4115405-A | 6-Nitro-or amino-4-chromanone oxime | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-09-19 | — | — | US | disclosed |