Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627341 | 0.84 | HSP90AB1 (0.36) | HTTHSP90AB1 | |
| SCHEMBL19422365 | 0.84 | HSP90AB1 (0.36) | HTTHSP90AA1HSP90AB1 | |
| SCHEMBL17576105 | 0.81 | HSP90AA1 (0.38) | HTTLMNAMAPTKMT2AHSP90AA1 | |
| SCHEMBL383476 | 0.78 | ALDH1A1 (0.41) | HTTPOLBMAPTKMT2AHSP90AA1 | |
| SCHEMBL6765323 | 0.78 | ALDH1A1 (0.50) | HTTPOLBLMNAMAPTKMT2A | |
| SCHEMBL7400206 | 0.78 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL1317017 | 0.78 | ALDH1A1 (0.50) | LMNA | |
| Benzene SCHEMBL10353060 | 0.72 | ALDH1A1 (0.46) | HTTLMNAMAPTKMT2A | |
| SCHEMBL27349521 | 0.71 | — | — | |
| SCHEMBL27564840 | 0.71 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |