SCHEMBL11543716

SCHEMBL11543716

CCOP(=O)(CCOC(C)(C(=O)c1ccccc1)c1ccccc1)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
CES1 P23141 1/20 0.39
POLB P06746 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
PRSS1 P07477 1/20 0.35
CTSG P08311 1/20 0.35
CTRB1 P17538 1/20 0.35
CMA1 P23946 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PPARD Q03181 1/20 0.35
NPC1 O15118 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11541009 0.87 CES1 (0.44) ALDH1A1TSHRCES1POLBSMN1; SMN2
SCHEMBL11540819 0.86 CES1 (0.50) ALDH1A1TSHRCES1POLBSMN1; SMN2
SCHEMBL11549441 0.86 CES1 (0.40) ALDH1A1TSHRCES1POLBSMN1; SMN2
SCHEMBL11547489 0.85 CES1 (0.39) ALDH1A1TSHRCES1POLBSMN1; SMN2
SCHEMBL11540699 0.84 CES1 (0.38) ALDH1A1TSHRCES1POLBSMN1; SMN2
SCHEMBL11547528 0.81 CES1 (0.45) ALDH1A1TSHRCES1POLBSMN1; SMN2
SCHEMBL13148475 0.80 CES1 (0.50) ALDH1A1TSHRCES1MAPTPRSS1
SCHEMBL11545780 0.79 CES1 (0.48) CES1SMN1; SMN2
SCHEMBL11543021 0.77 SMN1; SMN2 (0.38) ALDH1A1TSHRPOLBSMN1; SMN2MAPT
SCHEMBL9342063 0.77 CES1 (0.39) ALDH1A1TSHRCES1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4160794-A CURING OR POLYMERIZATION PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1979-07-10 US disclosed
US-4082821-A PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1978-04-04 US disclosed