Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540699 | 0.91 | CES1 (0.38) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11540819 | 0.86 | CES1 (0.50) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11549441 | 0.86 | CES1 (0.40) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11543716 | 0.85 | ALDH1A1 (0.39) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL9342063 | 0.85 | CES1 (0.39) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11588449 | 0.84 | CES1 (0.40) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11544876 | 0.83 | CETP (0.37) | SMN1; SMN2 | |
| SCHEMBL11542272 | 0.83 | SMN1; SMN2 (0.39) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL9346011 | 0.82 | CES1 (0.46) | CES1SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL7911425 | 0.82 | CES1 (0.49) | CES1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |