Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pirquinozol SCHEMBL635679 | 0.83 | ADORA3 (0.59) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11254079 | 0.81 | ADORA3 (0.56) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11548397 | 0.81 | ADORA3 (0.61) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11549605 | 0.81 | ADORA3 (0.54) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11288740 | 0.80 | ADORA3 (0.56) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11250103 | 0.80 | ADORA3 (0.58) | ADORA3HSD17B10 | |
| SCHEMBL11282330 | 0.80 | ADORA3 (0.62) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11287894 | 0.78 | ADORA3 (0.61) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11541876 | 0.77 | ADORA3 (0.52) | ADORA3HAVCR2HSD17B10 | |
| SCHEMBL11631361 | 0.77 | ADORA3 (0.52) | ADORA3HAVCR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179561-A | REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |