Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542932 | 0.82 | — | — | |
| SCHEMBL5521556 | 0.74 | PRMT1 (0.45) | ALDH1A1MAPTTSHR | |
| SCHEMBL5517612 | 0.71 | ATM (0.41) | TSHR | |
| SCHEMBL11741566 | 0.71 | — | — | |
| SCHEMBL4721360 | 0.67 | — | — | |
| SCHEMBL5007954 | 0.62 | TP53 (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL140259 | 0.60 | CA2 (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL9693129 | 0.60 | CA2 (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL9801330 | 0.58 | CA2 (0.46) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL9801336 | 0.58 | CA2 (0.46) | CA1CA2CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169094-A | Process for preparing aminoalkylpyrrolobenzoxazalkanes | AMERICAN HOECHST CORPORATION (US) | 1979-09-25 | — | — | US | disclosed |
| US-4169095-A | Process for preparing aminoalkylpyrrolobenzoxazalkanes | AMERICAN HOECHST CORPORATION (US) | 1979-09-25 | — | — | US | disclosed |
| US-4107187-A | Aminoalkylpyrrolobenzoxazalkanes | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107074-A | Process for preparing aminoalkylpyrrolobenzoxazalkanes | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4029672-A | Aminoalkylpyrrolobenzoxazalkanes | AMERICAN HOECHST CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |