Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545988 | 0.86 | HPGD (0.57) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11550738 | 0.85 | HTT (0.73) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| Diethylaniline SCHEMBL19065190 | 0.80 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1006444 | 0.79 | HTT (0.71) | HPGDMEN1KMT2AALDH1A1HTT | |
| SCHEMBL18275041 | 0.78 | RORC (0.66) | HPGD | |
| SCHEMBL4008336 | 0.77 | HPGD (0.59) | HPGDMAPTKMT2AALDH1A1ADRB2 | |
| SCHEMBL9809224 | 0.76 | HPGD (0.66) | HPGDMEN1KMT2AALDH1A1HTT | |
| SCHEMBL28652943 | 0.76 | MAPT (0.70) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14914 | 0.75 | MAPT (0.85) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL9121361 | 0.75 | MAPT (0.85) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |