Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583365 | 0.79 | TP53 (0.32) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL11540006 | 0.77 | TSHR (0.31) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL13629585 | 0.69 | TP53 (0.38) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL4520016 | 0.69 | TP53 (0.38) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL24452448 | 0.66 | TP53 (0.34) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL3138269 | 0.66 | TP53 (0.35) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL17236071 | 0.66 | TP53 (0.35) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL13992906 | 0.66 | TP53 (0.35) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL8068030 | 0.63 | MEN1 (0.39) | CYP3A4MEN1KMT2A | |
| SCHEMBL8838241 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156686-A | Catalytic reaction of alkenyl succinic anhydrides and olefins | CHEVRON RESEARCH COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4000163-A | Palladium catalyzed isomerization of alkenyl succinic anhydride and palladium catalyzed reaction of alkenyl succinic anhydride and olefines producing alpha-alkyl, β-alkenyl succinic anhydride | CHEVRON RESEARCH COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3989726-A | Platinum catalyzed isomerization of alkenyl succinic anhydrides | CHEVRON RESEARCH COMPANY (US) | 1976-11-02 | — | — | US | disclosed |