Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458027 | 0.89 | HSP90AA1 (0.45) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL11543476 | 0.87 | CYP3A4 (0.51) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL11544305 | 0.83 | HSP90AA1 (0.57) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL28608936 | 0.83 | HSP90AA1 (0.57) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL28602335 | 0.83 | HSP90AA1 (0.57) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL28920269 | 0.82 | HSP90AA1 (0.54) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL11086371 | 0.82 | GAA (0.44) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL20621487 | 0.81 | GAA (0.50) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL9737350 | 0.81 | GAA (0.47) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 | |
| SCHEMBL9737346 | 0.81 | GAA (0.47) | GAAHSD17B10HSP90AA1NPSR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160838-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-07-10 | — | — | US | disclosed |
| US-4079062-A | ANTIMICROBIAL, PLANT GROWTH REGULATORS; 1-(B-ARYL)ETHYL-1H-1,2,4-TRIAZOLE KETALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-03-14 | — | — | US | disclosed |