SCHEMBL28608936

SCHEMBL28608936

C[C@H]1COC(Cn2cncn2)(c2ccccc2)O1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 3/20 0.57
NPSR1 Q6W5P4 1/20 0.57
GAA P10253 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP3A4 P08684 7/20 0.47
THRB P10828 1/20 0.47
CYP19A1 P11511 2/20 0.39
CYP2C9 P11712 3/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11544305 1.00 HSP90AA1 (0.57) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL28602335 1.00 HSP90AA1 (0.57) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL9458158 0.90 HSP90AA1 (0.53) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL28604622 0.89 HSP90AA1 (0.59) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL28599786 0.89 HSP90AA1 (0.59) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL11545641 0.89 HSP90AA1 (0.59) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL11546179 0.89 HSP90AA1 (0.72) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL28619030 0.88 HSP90AA1 (0.58) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL28605860 0.88 HSP90AA1 (0.58) HSP90AA1NPSR1GAAHSD17B10CYP3A4
SCHEMBL28602217 0.88 HSP90AA1 (0.58) HSP90AA1NPSR1GAAHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234066-A Propiconazole-like compound and preparation method and application thereof 浙江工业大学 2021-08-10 CN disclosed