Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155188 | 1.00 | MMP2 (0.38) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL19910775 | 0.88 | CHRM2 (0.37) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL7143154 | 0.88 | HSD17B10 (0.38) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL16754873 | 0.88 | HSD17B10 (0.38) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL8609251 | 0.88 | MMP2 (0.40) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL8607697 | 0.88 | MMP2 (0.40) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL3382551 | 0.88 | HSD17B10 (0.38) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL4418512 | 0.88 | HSD17B10 (0.38) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL8990042 | 0.88 | HSD17B10 (0.38) | MMP2ANPEPNR1H2NR1H3CHRM2 | |
| SCHEMBL5691732 | 0.85 | MMP2 (0.48) | MMP2ANPEPNR1H2NR1H3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893103-B2 | Dipeptidyl peptidase IV (DPP-IV); industrial scale process of making antidiabetics such as (2S,4S)-1-{2-[(3SR,1RS)-3-(1H-1,2,4-Triazol-1-ylmethyl)cyclopentylamino]acetyl}-4-fluoro-pyrrolidine-2-carbonitrile starting from ethyl glyoxalate and 3-(1H-1,2,4-triazol-1-ylmethyl)cyclopententylamine for example | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2011-02-22 | — | — | US | disclosed |
| EP-2035395-A2 | NOVEL PROCESSES FOR THE PREPARATION OF DPP IV INHIBITORS | Glenmark Pharmaceuticals S.A. (CH) | 2009-03-18 | — | — | EP | disclosed |
| US-20080076818-A1 | NOVEL PROCESSES FOR THE PREPARATION OF DPP IV INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-03-27 | — | — | US | disclosed |
| WO-2008001195-A2 | NOVEL PROCESSES FOR THE PREPARATION OF DPP IV INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076818-A1 | NOVEL PROCESSES FOR THE PREPARATION OF DPP IV INHIBITORS | DPP4, DPP7, DPP3 | MMP2 39/4885ANPEP 61/4885NR1H2 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.