Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089743 | 0.88 | CYP3A4 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL160983 | 0.83 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL10624650 | 0.83 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11881242 | 0.83 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL1769087 | 0.83 | TSHR (0.50) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL5693642 | 0.83 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL940009 | 0.81 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL4260306 | 0.79 | CYP3A4 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL2117825 | 0.78 | CYP3A4 (0.54) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL15430 | 0.76 | CYP3A4 (0.70) | CYP3A4TSHRMAPK1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140787-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |