SCHEMBL160983

SCHEMBL160983

O=C=Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
HTR3E A5X5Y0 1/20 0.47
HTR3B O95264 1/20 0.47
PLAU P00749 1/20 0.47
HTR3A P46098 1/20 0.47
HTR3D Q70Z44 1/20 0.47
HTR3C Q8WXA8 1/20 0.47
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TRPA1 O75762 1/20 0.39
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KIF11 P52732 6/20 0.38
PTGS2 P35354 2/20 0.38
EPHX2 P34913 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8591004 0.90 CYP3A4 (0.42) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL10546748 0.89 CYP3A4 (0.41) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL10624650 0.86 CYP3A4 (0.50) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL940009 0.84 CYP3A4 (0.48) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL9484832 0.84 CA1 (0.45) PLAUNOS1KIF11PTGS2NPSR1
SCHEMBL11544759 0.83 CYP3A4 (0.47) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL4260306 0.83 CYP3A4 (0.47) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL11089743 0.83 CYP3A4 (0.47) CYP3A4TSHRHTR3EHTR3BPLAU
SCHEMBL2117825 0.81 CYP3A4 (0.54) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL19707397 0.81 HTR3E (0.50) CYP3A4TSHRHTR3EHTR3BPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2295 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4721152-A2 ORGANIC THIN FILM COATINGS FOR BATTERY MATERIALS Coreshell Technologies, Inc. (US) 2026-04-08 EP claimed
CN-115515998-B Synthesis of polyurethanes by chain growth copolymerization 伊夫·雅努 2025-06-24 CN claimed
CN-119819277-B Beta-cyclodextrin derivative chiral stationary phase based on BINAM and preparation method and application thereof 昆明医科大学 2025-05-27 CN claimed
CN-119819277-A Beta-cyclodextrin derivative chiral stationary phase based on BINAM and preparation method and application thereof 昆明医科大学 2025-04-15 CN claimed
WO-2024249841-A2 ORGANIC THIN FILM COATINGS FOR BATTERY MATERIALS CORESHELL TECHNOLOGIES, INC. (US) 2024-12-05 WO claimed
US-20240332628-A1 Silicon-Based Energy Storage Devices With Electrolyte Containing Cyanate Based Compounds ENEVATE CORP (US) 2024-10-03 US claimed
CN-118419908-A Preparation method of eucalyptus-based hard carbon negative electrode material 浙江鑫钠新材料科技有限公司 2024-08-02 CN claimed
CN-118253468-A Method for preparing coating, coating and device 江苏菲沃泰纳米科技股份有限公司 2024-06-28 CN claimed
CN-116217486-B Fluorescent compound and preparation method and application thereof 厦门大学 2024-05-14 CN claimed
CN-118016995-A Non-aqueous electrolyte containing aromatic isocyanate and lithium ion battery 诺莱特电池材料(苏州)有限公司 2024-05-10 CN claimed
WO-2000048964-A1 METALLIC OR CERAMIC POWDER WITH A PROTECTIVE COATING H. C. STARCK GMBH & CO. KG (DE) 2000-08-24 WO claimed
CN-1227548-A Substituted p-trifluoromethylphenyluracils BAYER AG (DE) 1999-09-01 CN claimed
EP-0923562-A1 SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS BAYER AG (DE) 1999-06-23 EP claimed
WO-1998006706-A1 SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 1998-02-19 WO claimed
US-4748277-A FLUORINATION AND HYDROLYSIS OF TRIHALOMETHYLPHENYL ISOCYANATE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-31 US claimed
EP-0129214-B1 METHOD FOR THE PREPARATION OF BENZENAMINES OCCIDENTAL CHEMICAL CORPORATION (US) 1986-10-29 EP claimed
EP-0129214-A1 Method for the preparation of benzenamines OCCIDENTAL CHEMICAL CORPORATION (US) 1984-12-27 EP claimed
US-4481370-A REACTING HYDROGEN FLUORIDE WITH A PHENYL CARBAMIC FLUORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-11-06 US claimed
US-4359426-A Process for the production of aromatic isocyanates containing aromatically bound sulfochloride groups BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US claimed
EP-0003766-A1 N-(omega-chloroalcanoyl)-N'-trifluoromethylphenyl-urea, preparation thereof and use thereof as plant-protecting agents BAYER AG (DE) 1979-09-05 EP claimed