Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506808 | 0.94 | PTPN5 (0.57) | PTPN5KMT2APARP10NR1H4CYP3A4 | |
| SCHEMBL25565730 | 0.82 | ALDH1A3 (0.48) | PTPN5KMT2APARP10NR1H4CYP3A4 | |
| SCHEMBL10934190 | 0.82 | ALDH1A3 (0.48) | PTPN5KMT2APARP10NR1H4CYP3A4 | |
| SCHEMBL799946 | 0.82 | NR1H4 (0.57) | PTPN5KMT2APARP10NR1H4CYP3A4 | |
| SCHEMBL31664426 | 0.80 | HRH3 (0.42) | PTPN5NR1H4HRH3MAPT | |
| Hydrogen Peroxide SCHEMBL28902806 | 0.78 | KMT2A (0.70) | PTPN5KMT2APARP10ALDH1A3POLB | |
| SCHEMBL125543 | 0.78 | ALDH1A3 (0.64) | PTPN5KMT2APARP10ALDH1A3POLB | |
| SCHEMBL10876942 | 0.78 | NR1H4 (0.47) | PTPN5KMT2APARP10NR1H4CYP3A4 | |
| SCHEMBL12541779 | 0.78 | ESR1 (0.53) | PTPN5KMT2APARP10NR1H4CYP3A4 | |
| SCHEMBL8636388 | 0.78 | ESR1 (0.61) | PTPN5KMT2APARP10NR1H4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015037243-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDANTOIN COMPOUND | 興和株式会社 (JP) | 2015-03-19 | — | — | WO | disclosed |
| US-4148809-A | Process for preparing dl-cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones | ELI LILLY AND COMPANY (US) | 1979-04-10 | — | — | US | disclosed |