Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15677148 | 0.82 | MAPT (0.63) | MAPTGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11547071 | 0.82 | CYP1A2 (0.51) | MAPTLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL2680437 | 0.79 | LMNA (0.43) | LMNASMN1; SMN2KDM4ERAB9AALDH1A1 | |
| SCHEMBL15677170 | 0.78 | MAPT (0.58) | MAPTGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL822725 | 0.76 | MAPT (0.72) | MAPTGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11937238 | 0.76 | TP53 (0.54) | MAPTLMNASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL15677168 | 0.76 | MAPT (0.57) | MAPTGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL14922116 | 0.76 | CYP2D6 (0.59) | MAPTGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL31098425 | 0.75 | LMNA (0.59) | MAPTGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL13761600 | 0.75 | AR (0.69) | MAPTGAALMNAHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144351-A | ANTICHOLESTEROL | KLINGE PHARMA GMBH & CO. (DE) | 1979-03-13 | — | — | US | claimed |