Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 16/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.54 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544830 | 1.00 | PTGS1 (0.65) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11544218 | 0.99 | PTGS1 (0.67) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11544215 | 0.99 | PTGS1 (0.67) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11545114 | 0.96 | PTGS1 (0.70) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11545111 | 0.96 | PTGS1 (0.70) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11543796 | 0.84 | PTGS1 (0.49) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11543792 | 0.84 | PTGS1 (0.49) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11548462 | 0.83 | PTGS1 (0.92) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9063273 | 0.82 | PTGS1 (0.95) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Arginine SCHEMBL11544512 | 0.81 | PTGS1 (0.47) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161538-A | 4-(2-OXO- OR HYDROXIMINO-CYCLOALKAN-1-YLMETHYL)-PHENYLACETIC ACID, ANTIINFLAMMATORY AGENTS | SANKYO COMPANY LIMITED (JP) | 1979-07-17 | — | — | US | disclosed |