Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543792 | 1.00 | PTGS1 (0.49) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11544215 | 0.85 | PTGS1 (0.67) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11544218 | 0.85 | PTGS1 (0.67) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11544831 | 0.84 | PTGS1 (0.65) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11544830 | 0.84 | PTGS1 (0.65) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11545111 | 0.83 | PTGS1 (0.70) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11545114 | 0.83 | PTGS1 (0.70) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9141017 | 0.82 | CYP4Z1 (0.42) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9141011 | 0.82 | CYP4Z1 (0.42) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL8846169 | 0.82 | PTGS2 (0.73) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161538-A | 4-(2-OXO- OR HYDROXIMINO-CYCLOALKAN-1-YLMETHYL)-PHENYLACETIC ACID, ANTIINFLAMMATORY AGENTS | SANKYO COMPANY LIMITED (JP) | 1979-07-17 | — | — | US | disclosed |