Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540797 | 0.88 | SCN9A (0.46) | NPSR1 | |
| SCHEMBL11544501 | 0.87 | FFAR1 (0.53) | TTRFFAR1TDP1MRGPRX4MAPT | |
| SCHEMBL11544620 | 0.86 | FFAR1 (0.48) | TTRFFAR1TDP1MRGPRX4MAPT | |
| SCHEMBL28275126 | 0.81 | TDP1 (0.60) | TTRFFAR1TDP1MRGPRX4MAPT | |
| SCHEMBL1283828 | 0.81 | FFAR1 (0.57) | TTRFFAR1TDP1MRGPRX4MAPT | |
| SCHEMBL10277125 | 0.80 | PTGS1 (0.46) | MAPTRAB9A | |
| SCHEMBL10277127 | 0.80 | PTGS1 (0.46) | MAPTRAB9A | |
| SCHEMBL10277124 | 0.80 | PTGS1 (0.46) | MAPTRAB9A | |
| SCHEMBL11487617 | 0.79 | FFAR1 (0.48) | TTRFFAR1TDP1MRGPRX4MAPT | |
| SCHEMBL11487620 | 0.79 | FFAR1 (0.48) | TTRFFAR1TDP1MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |