Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11307929 | 1.00 | LMNA (0.67) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL11152373 | 1.00 | LMNA (0.67) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL11170563 | 1.00 | LMNA (0.67) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL11765690 | 1.00 | LMNA (0.67) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL312284 | 1.00 | LMNA (0.67) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL10771333 | 1.00 | LMNA (0.67) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL28115521 | 0.95 | LMNA (0.60) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL9149417 | 0.95 | LMNA (0.60) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL3673826 | 0.95 | FFAR3 (0.70) | LMNAFFAR3LCKFYNTSHR | |
| Benzene SCHEMBL11551346 | 0.95 | LMNA (0.60) | LMNAFFAR3LCKFYNTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179503-A | DIURETICS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-12-18 | — | — | US | disclosed |
| EP-0005365-A1 | Pyrano and thiopyrano (3,4-b) indole derivatives, processes for their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-11-14 | — | — | EP | disclosed |