Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541426 | 0.89 | PDE3B (0.35) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL19807936 | 0.82 | SMN1; SMN2 (0.41) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11541492 | 0.81 | CYP1A1 (0.39) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL11542463 | 0.78 | GAA (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL11544043 | 0.77 | DAPK3 (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL20595719 | 0.77 | CYP1A2 (0.39) | ALDH1A1GLAMEN1KMT2ADDB1 | |
| SCHEMBL11542960 | 0.77 | CRBN (0.33) | KDM4ESMN1; SMN2DDB1CRBNALOX5 | |
| SCHEMBL11544625 | 0.76 | MAPT (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL11542347 | 0.75 | TP53 (0.40) | ALDH1A1SMN1; SMN2CRBNALOX5NPC1 | |
| SCHEMBL32688313 | 0.75 | CRBN (0.44) | KDM4EALDH1A1HPGDDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |