Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24149842 | 0.91 | TRPV1 (0.46) | RXFP1HSP90AA1HSP90AB1GABRB1GABRB2 | |
| SCHEMBL118218 | 0.86 | CASP6 (0.57) | CASP6ALDH1A1HPGDCA12CA1 | |
| SCHEMBL117162 | 0.83 | CASP6 (0.43) | RXFP1CASP6ALDH1A1HPGDCA12 | |
| SCHEMBL8923098 | 0.80 | PLAU (0.54) | ALDH1A1HPGDCA12CA1CA2 | |
| SCHEMBL116199 | 0.80 | EPHX2 (0.44) | RXFP1CASP6ALDH1A1HPGDLMNA | |
| SCHEMBL27453735 | 0.79 | RXFP1 (0.46) | RXFP1CASP6ALDH1A1HPGDTRPV1 | |
| SCHEMBL30077817 | 0.79 | RXFP1 (0.46) | RXFP1CASP6ALDH1A1HPGDTRPV1 | |
| SCHEMBL487112 | 0.79 | TRPV1 (0.44) | RXFP1HSP90AA1HSP90AB1ALDH1A1HPGD | |
| SCHEMBL14059000 | 0.79 | CASP6 (0.68) | RXFP1CASP6HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL6242484 | 0.78 | KAT6A (0.47) | RXFP1ALDH1A1KAT6ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| CN-102414175-A | Insecticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-04-11 | — | — | CN | disclosed |
| EP-2424838-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer CropScience AG (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124845-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010124845-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | WO | disclosed |
| US-7001900-B2 | Azabicyclic compounds for the treatment of disease | PFIZER INC. (US) | 2006-02-21 | — | — | US | disclosed |
| EP-1478646-A1 | AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20030236270-A1 | Azabicyclic compounds for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-12-25 | — | — | US | disclosed |
| WO-2003072578-A1 | AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | DDT, AADAC, AHR | RXFP1 2234/4885CASP6 613/4885HSP90AA1 1623/4885 |
| US-20030236270-A1 | Azabicyclic compounds for the treatment of disease | MALT1, TPMT, CYP2B6 | RXFP1 3198/4885CASP6 1594/4885HSP90AA1 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.