Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544091 | 0.89 | POLB (0.38) | ALDH1A1SMN1; SMN2HPGDRAB9APOLB | |
| SCHEMBL11542347 | 0.84 | TP53 (0.40) | ALDH1A1SMN1; SMN2RAB9APOLBTP53 | |
| SCHEMBL11542181 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HPGDRAB9APOLB | |
| SCHEMBL1713613 | 0.78 | CRBN (0.44) | ALDH1A1HPGDPOLBKDM4ECRBN | |
| SCHEMBL32688313 | 0.78 | CRBN (0.44) | ALDH1A1HPGDPOLBKDM4ECRBN | |
| SCHEMBL11542870 | 0.76 | ALPI (0.43) | ALDH1A1SMN1; SMN2HPGDRAB9APOLB | |
| SCHEMBL11544625 | 0.73 | MAPT (0.36) | ALDH1A1SMN1; SMN2LMNACRBNMEN1 | |
| SCHEMBL11546400 | 0.70 | TYMS (0.36) | SMN1; SMN2HPGDLMNATP53CRBN | |
| SCHEMBL11543677 | 0.68 | DDB1 (0.32) | TP53CRBN | |
| SCHEMBL20595719 | 0.68 | CYP1A2 (0.39) | ALDH1A1RAB9AGLAHTTCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |