Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.74 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.57 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646401 | 0.87 | MEN1 (0.73) | PARP1PARP10KMT2AMEN1PARP15 | |
| SCHEMBL2562988 | 0.85 | SMN1; SMN2 (0.59) | PARP1PARP10KMT2AMEN1ALDH1A1 | |
| SCHEMBL30716404 | 0.85 | KMT2A (0.71) | PARP1PARP10KMT2AMEN1PARP14 | |
| SCHEMBL5524698 | 0.85 | KMT2A (0.71) | PARP1PARP10KMT2AMEN1PARP14 | |
| SCHEMBL18671651 | 0.85 | KMT2A (0.87) | PARP1PARP10KMT2AMEN1PARP15 | |
| SCHEMBL8752439 | 0.84 | MEN1 (0.66) | PARP1PARP10KMT2AMEN1ALDH1A1 | |
| SCHEMBL17933240 | 0.83 | MEN1 (0.57) | PARP1PARP10KMT2AMEN1ALDH1A1 | |
| SCHEMBL14567079 | 0.83 | KMT2A (0.88) | PARP1PARP10KMT2AMEN1PARP15 | |
| SCHEMBL895009 | 0.83 | PARP1 (0.63) | PARP1PARP10KMT2AMEN1PARP15 | |
| SCHEMBL29761319 | 0.83 | PARP1 (0.63) | PARP1PARP10KMT2AMEN1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |