Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SQLE | Q14534 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545440 | 1.00 | KMT2A (0.43) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL11547121 | 0.85 | KMT2A (0.46) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL11547124 | 0.85 | KMT2A (0.46) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL11549692 | 0.84 | KMT2A (0.50) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL11549688 | 0.84 | KMT2A (0.50) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL11547685 | 0.82 | SQLE (0.32) | SQLEFNTAFNTB | |
| SCHEMBL11547687 | 0.82 | SQLE (0.32) | SQLEFNTAFNTB | |
| SCHEMBL11552338 | 0.80 | KMT2A (0.64) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL2456517 | 0.80 | KMT2A (0.50) | KMT2ASQLEMEN1CYP3A4ALOX15 | |
| SCHEMBL2456513 | 0.80 | KMT2A (0.50) | KMT2ASQLEMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137273-A | INSECTICIDES, CHEMICAL INTERMEDIATES | ZOECON CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
| US-4002647-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-3957763-A | PHENYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |