Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.45 |
| ▸ | SQLE | Q14534 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549692 | 1.00 | KMT2A (0.50) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL11547598 | 0.87 | SQLE (0.38) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL11547600 | 0.87 | SQLE (0.38) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL11549382 | 0.86 | KMT2A (0.50) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL2456513 | 0.86 | KMT2A (0.50) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL2456517 | 0.86 | KMT2A (0.50) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL11549385 | 0.86 | KMT2A (0.50) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL755511 | 0.85 | — | — | |
| SCHEMBL755510 | 0.85 | — | — | |
| SCHEMBL11545443 | 0.84 | KMT2A (0.43) | KMT2AALOX15MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137273-A | INSECTICIDES, CHEMICAL INTERMEDIATES | ZOECON CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
| US-4005150-A | Phenyl ethers having juvenile hormone activity | CESKOSLOVENSKA AKADEMIE VED (CS) | 1977-01-25 | — | — | US | disclosed |
| US-4002647-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-3962428-A | JUVENILE HORMONE | HOFFMANN-LA ROCHE INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3961051-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3957763-A | PHENYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3950328-A | INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |