Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.59 |
| ▸ | GAA | P10253 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545508 | 1.00 | MAPT (0.59) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL3067385 | 0.84 | MAPT (0.64) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL3067386 | 0.84 | MAPT (0.64) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL11544435 | 0.83 | GAA (0.56) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL11544430 | 0.83 | GAA (0.56) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL6130732 | 0.77 | CA1 (0.69) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL6130737 | 0.77 | CA1 (0.69) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL11545493 | 0.72 | MAPT (0.86) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL11545496 | 0.72 | MAPT (0.86) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL4043916 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163793-A | Use of certain thiophenecarbaldehyde phenylhydrazones as fungicides | SHELL OIL COMPANY (US) | 1979-08-07 | — | — | US | claimed |
| US-4163793-A | Use of certain thiophenecarbaldehyde phenylhydrazones as fungicides | SHELL OIL COMPANY (US) | 1979-08-07 | — | — | US | disclosed |