Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545932 | 0.97 | NPC1 (0.61) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL11545921 | 0.95 | NPC1 (0.68) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL11539115 | 0.92 | NPC1 (0.56) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL7335153 | 0.91 | NPC1 (0.54) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL248876 | 0.89 | NPC1 (0.53) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL907915 | 0.89 | NPC1 (0.56) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL7408359 | 0.89 | NPC1 (0.56) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL215008 | 0.89 | NPC1 (0.56) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL30967467 | 0.89 | NPC1 (0.56) | NPC1RAB9ARECQLKDM4EMAPT | |
| SCHEMBL11544509 | 0.88 | NPC1 (0.53) | NPC1RAB9ARECQLKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |