Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545895 | 0.85 | MAPK8 (0.40) | MAPK8MAPK9ALDH1A1KDM4ECASP1 | |
| SCHEMBL11545713 | 0.82 | MAPK8 (0.43) | MAPK8MAPK9ALDH1A1KDM4ECASP1 | |
| SCHEMBL11543962 | 0.76 | L3MBTL1 (0.37) | MAPK8MAPK9ALDH1A1MAPTHPGD | |
| SCHEMBL11546629 | 0.75 | KMT2A (0.40) | MAPK8MAPK9MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL11544407 | 0.69 | MAPT (0.50) | ALDH1A1CASP1CASP7HSD17B10MAPT | |
| SCHEMBL11546363 | 0.68 | MAPK8 (0.45) | MAPK8MAPK9CASP1CASP7HSD17B10 | |
| SCHEMBL19116481 | 0.67 | MAPK8 (0.39) | MAPK8MAPK9ALDH1A1KDM4ECASP1 | |
| SCHEMBL11698200 | 0.65 | KMT2A (0.41) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL20551405 | 0.65 | PIK3CG (0.41) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL1145455 | 0.64 | MAPK8 (1.00) | MAPK8MAPK9PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163846-A | HERBICIDES | FISONS LIMITED (GB) | 1979-08-07 | — | — | US | disclosed |