Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6114713 | 0.82 | TLR8 (0.45) | CYP11B2CYP11B1PRKCZTLR8PARP1 | |
| Phosphine SCHEMBL28863280 | 0.81 | CNR2 (0.46) | TLR8CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2701240 | 0.78 | LIPG (0.50) | TLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6114616 | 0.78 | TLR8 (0.46) | KCNH2CYP11B2CYP11B1TLR8CYP3A4 | |
| SCHEMBL11032001 | 0.78 | KCNA5 (0.56) | KCNA5KCNH2CYP11B2CYP11B1PRKCZ | |
| SCHEMBL6058810 | 0.78 | CNR1 (0.49) | KCNH2TLR8CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13505762 | 0.78 | TLR8 (0.41) | KCNH2TLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6115451 | 0.76 | MAPT (0.45) | KCNH2CYP11B2CYP11B1TLR8CYP3A4 | |
| SCHEMBL6115304 | 0.76 | MAPT (0.45) | KCNH2CYP11B2CYP11B1TLR8CYP3A4 | |
| SCHEMBL6114726 | 0.76 | MAPT (0.45) | KCNH2CYP11B2CYP11B1TLR8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175191-A | 4-Phenyl isoquinolines | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |