Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.81 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.81 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.81 |
| ▸ | PTGIR | P43119 | 3/20 | 0.81 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.81 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.81 |
| ▸ | PTGFR | P43088 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
| ▸ | PGR | P06401 | 1/20 | 0.81 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.63 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546236 | 1.00 | PTGER4 (0.81) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| SCHEMBL11776804 | 1.00 | PTGER4 (0.81) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| SCHEMBL11775424 | 1.00 | PTGER4 (0.81) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL23352922 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL24340817 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL24223591 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL24727254 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL23352988 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL23352791 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 | |
| Dinoprostone SCHEMBL23353214 | 0.90 | PTGIR (1.00) | PTGER4TBXA2RPTGER2PTGIRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170710-A | BRONCHODILATORS, HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-10-09 | — | — | US | disclosed |
| US-4156094-A | Prostaglandin derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4076730-A | BRONCHODILATORS, HYPOTENSIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |
| US-4067898-A | Prostaglandin derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4034002-A | Prostaglandin derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |