Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | FABP6 | P51161 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546301 | 0.86 | TYMS (0.52) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL11363771 | 0.85 | PLAU (0.59) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL23717447 | 0.82 | PLAU (0.56) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL11546882 | 0.81 | TYMS (0.63) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL16809191 | 0.80 | ALDH1A1 (0.58) | TYMSALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10955757 | 0.79 | PLAU (0.53) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL7257713 | 0.79 | CYP1A2 (0.56) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL8502461 | 0.79 | HPGD (0.51) | TYMSHTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL8081175 | 0.79 | ALDH1A1 (0.44) | TYMSALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL24117418 | 0.78 | MEN1 (0.53) | TYMSPLAUHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |