Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15339524 | 0.81 | GAA (0.38) | IDO1CDC7DBF4TDP1SMN1; SMN2 | |
| SCHEMBL11989001 | 0.70 | IDO1 (0.41) | MAPTIDO1CDC7DBF4ALDH1A1 | |
| SCHEMBL5185462 | 0.67 | ALDH1A1 (0.53) | TSHRHPGDNPSR1MAPTIDO1 | |
| SCHEMBL11976534 | 0.67 | IDO1 (0.39) | IDO1CDC7DBF4 | |
| SCHEMBL15339506 | 0.67 | CCR1 (0.35) | IDO1CDC7DBF4TDP1SMN1; SMN2 | |
| SCHEMBL862535 | 0.65 | GAA (0.40) | CDC7DBF4TDP1SMN1; SMN2HTT | |
| SCHEMBL15339507 | 0.64 | HTT (0.37) | HPGDMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL262306 | 0.64 | ALDH1A1 (0.56) | TSHRHPGDMAPTALDH1A1TDP1 | |
| SCHEMBL15339508 | 0.64 | KDM4E (0.37) | HPGDMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL77350 | 0.63 | IDO1 (0.37) | IDO1CDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167506-A | Diazaphenalene derivatives and resin containing color compositions | TEIJIN LIMITED (JP) | 1979-09-11 | — | — | US | disclosed |