Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30371912 | 0.83 | CYP2C19 (0.61) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL7056269 | 0.83 | CYP2C19 (0.49) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL7824476 | 0.83 | CYP2C19 (0.49) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL7824473 | 0.83 | CYP2C19 (0.49) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL29211124 | 0.80 | CYP2C19 (0.46) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL909284 | 0.80 | CYP2C19 (0.53) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL7830236 | 0.80 | CYP2C19 (0.53) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL28408396 | 0.80 | CYP2C19 (0.53) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL908468 | 0.78 | CYP2C19 (0.52) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL5329154 | 0.78 | CYP2C19 (0.47) | CYP2C19LMNAMAPK1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139537-A | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds | COOPER LABORATORIES, INC. (US) | 1979-02-13 | — | — | US | disclosed |