Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909284 | 1.00 | CYP2C19 (0.53) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL908468 | 0.98 | CYP2C19 (0.52) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL2364634 | 0.88 | CYP2C19 (0.50) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL962850 | 0.88 | TBXAS1 (0.52) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL11637533 | 0.88 | CYP2C19 (0.44) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL30371912 | 0.87 | CYP2C19 (0.61) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL8868237 | 0.86 | TBXAS1 (0.55) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL908467 | 0.86 | CYP2C19 (0.43) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL22397201 | 0.84 | POLB (0.53) | CYP2C19CYP2D6LMNAPOLBMEN1 | |
| SCHEMBL28223379 | 0.84 | EPHX1 (0.59) | CYP2C19CYP2D6SRCLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500864-B1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| US-5292749-A | Quinuclidine derivatives; bronchodilator agents, treatment of respiratory system disorders | PFIZER INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0500864-A1 | ANTIMUSCARINIC BRONCHODILATORS | Pfizer Limited (GB) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004346-A1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |