Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729283 | 0.97 | TDP1 (0.48) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL8416807 | 0.85 | POLB (0.39) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL11940979 | 0.82 | TDP1 (0.40) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL8419049 | 0.82 | TDP1 (0.43) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL27959737 | 0.80 | SMN1; SMN2 (0.42) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL1900380 | 0.80 | CPB1 (0.39) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL630577 | 0.80 | TDP1 (0.48) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| Ammonia Solution, Strong SCHEMBL2546319 | 0.79 | TDP1 (0.42) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL27872253 | 0.79 | CPB1 (0.38) | TDP1CPB1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL7720554 | 0.78 | TDP1 (0.46) | TDP1CPB1SMN1; SMN2POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172207-A | Process for mercaptoalkanedicarboxylic acid esters | MACK GERRY P | 1979-10-23 | — | — | US | disclosed |