Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155208 | 0.80 | MAPT (0.48) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL21881930 | 0.80 | AKT2 (0.43) | MAPTLMNACYP3A4NOTUMSMN1; SMN2 | |
| SCHEMBL9643716 | 0.78 | MAPT (0.46) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL31555363 | 0.78 | MAPT (0.40) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL24391129 | 0.76 | CYP3A4 (0.43) | MAPTKDM4ECYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL28467302 | 0.76 | CYP2A6 (0.31) | — | |
| SCHEMBL12902949 | 0.76 | MAPT (0.56) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL21652623 | 0.76 | MAPT (0.56) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL29690567 | 0.76 | MAPT (0.56) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL16429763 | 0.75 | IMPDH2 (0.49) | MAPTLMNAKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002901-A1 | Process for substituting and dequaternizing pyridyl-ethyl quaternary salts of pyridine and bipyridine bases | REILLY INDUSTRIES, INC. (US) | 1979-07-11 | — | — | EP | disclosed |