SCHEMBL11547288

SCHEMBL11547288

C[Sn]C.O=C(CS)OCCCCOC(=O)CS

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.45
TSHR P16473 3/20 0.44
HSD17B10 Q99714 1/20 0.44
RAD52 P43351 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
FAAH O00519 1/20 0.37
HTR2C P28335 1/20 0.36
DGKA P23743 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTT P42858 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
CYP3A4 P08684 1/20 0.33
EPHX1 P07099 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
ACHE P22303 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11543999 0.98 NAAA (0.48) NAAATSHRHSD17B10RAD52NPSR1
SCHEMBL11549076 0.95 TSHR (0.44) NAAATSHRHSD17B10RAD52NPSR1
SCHEMBL11543313 0.90 TSHR (0.48) NAAATSHRHSD17B10DGKAALDH1A1
SCHEMBL60931 0.90 NAAA (0.46) NAAATSHRHSD17B10RAD52NPSR1
SCHEMBL16447946 0.90 NAAA (0.62) NAAATSHRRAD52NPSR1FAAH
SCHEMBL11152865 0.90 NAAA (0.62) NAAATSHRRAD52NPSR1FAAH
SCHEMBL11546905 0.90 NAAA (0.62) NAAATSHRRAD52NPSR1FAAH
SCHEMBL97045 0.87 NAAA (0.50) NAAATSHRHSD17B10RAD52NPSR1
SCHEMBL11585668 0.87 NAAA (0.50) NAAATSHRHSD17B10RAD52NPSR1
SCHEMBL96893 0.87 NAAA (0.50) NAAATSHRHSD17B10RAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed