Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510778 | 0.79 | — | — | |
| SCHEMBL10587921 | 0.72 | KMT2A (0.37) | LMNAKMT2A | |
| SCHEMBL18097396 | 0.71 | KMT2A (0.45) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL11547434 | 0.71 | MEN1 (0.43) | LMNANPSR1KMT2A | |
| SCHEMBL9025506 | 0.71 | KMT2A (0.36) | LMNANPSR1KMT2A | |
| SCHEMBL5722206 | 0.71 | KMT2A (0.33) | KMT2A | |
| SCHEMBL10896169 | 0.70 | KMT2A (0.37) | TSHRSMN1; SMN2KMT2A | |
| SCHEMBL11549964 | 0.69 | MEN1 (0.31) | SMN1; SMN2KMT2A | |
| SCHEMBL11349525 | 0.68 | DAO (0.35) | KMT2A | |
| SCHEMBL11506417 | 0.67 | PTGDR2 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001113-A1 | Thienothiazine derivatives, their preparation and compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-03-21 | — | — | EP | disclosed |